Effects of probiotic and alpha-lipoic acid supplements, separately or in combination on the anthropometric indicators and maintenance of weight in overweight individuals

Background & aims Weight loss after proper diet is one of the main topics in nutrition. This study was designed to evaluate effects probiotic and alpha-Lipoic acid (ALA) supplements on anthropometric indicators maintenance weight overweight individuals. Methods consisted two phases (8 weeks) (16 weeks). Eighty-eight participants were randomly divided into 4 groups phase 1: isocaloric with (500 mg), an ALA (600 mg) probiotic, placebo. In 2, received a normal mentioned supplements. beginning, end 1, at weight, body mass index (BMI), waist circumference (WC), hip (HC), fat percentage, blood pressure (BP) measured. Also, 10 cc samples taken from subjects measure C-reactive protein (CRP). Data analyzed using SPSS software. Results At phases, differences changes + group significant WC, CRP factors when compared other (P < 0.05). study, maintain reduced significantly higher than Conclusion According findings, probiotics supplementation help decreased adhering diet. may be due reduction inflammation. Trial registration (IRCT20141025019669N10).